Subjects were given a sugar pill. They were told it was a sugar pill. They were told that sugar pills are not medicine. And yet they had better outcomes than the control group who were not treated at all.
Edzard Ernst, a professor of complementary medicine at the University of Exeter, says, “This is an elegant study which suggests that the ritual of giving a patient a remedy is clinically effective, even if that patient has been told that the remedy is a placebo.” Kaptchuk himself says, “I suspect that just performing “the ritual of medicine” could have activated or primed self-healing mechanisms.” And Amir Raz, a neuroscientist who studies placebos at McGill University, adds, “Scientific reports make it clear, even if strange and counterintuitive, that receiving – rather than the actual content of – medical treatment can trigger and propel a healing process.”
Notably, the patients (apparently even the control group) were told about the psychology of the placebo effect.
They told the patients that “placebo pills, something like sugar pills, have been shown in rigorous clinical testing to produce significant mind-body self-healing processes.” And they explained: that “the placebo effect is powerful; the body can automatically respond to taking placebo pills like Pavlov’s dogs who salivated when they heard a bell; a positive attitude helps but is not necessary; and taking the pills faithfully is critical.”
There are many caveats and open questions, the full article is worth a read.

10 comments
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December 23, 2010 at 9:36 am
the weakonomist
I need placebo coffee and a placebo to sweeten it. Has there ever been any study on the medical effects of taking sugar pills?
December 23, 2010 at 10:23 am
jeff
I guess now there is. But maybe the control should have been sugar pills secretly given.
December 23, 2010 at 9:41 am
k
what about comparison across different treatments? it would be nice if those treated with an actual pill got better outcomes than with the placebo.
December 23, 2010 at 9:42 am
k
btw, they only had a total of 80 people. this is not very large sample size.
December 23, 2010 at 9:54 am
Andy
I worry about the Lucas Critique.
December 24, 2010 at 10:42 pm
Shrikant
More damning evidence of how homeopathy works? 🙂
December 28, 2010 at 5:35 am
Broolaitartow
Hi:
I recently registered with cheeptalk.wordpress.com.
I’m hoping to go looking around a lttle bit and come across interesting people and discover a couple of ideas.
I’m hoping this isn’t in a bad category. Please forgive me if it does.
——————–
KIRK ACOSTA
Music Director
December 28, 2010 at 8:33 am
jeffrey dach md
Another placebo effect: A study published in JAMA reported that SSRI antidepressants are no better than placebo for most cases of depression. The authors reviewed 30 years of data and concluded that “the benefit of antidepressant medication compared with placebo may be minimal or nonexistent in patients with mild or moderate symptoms”.
ref JAMA 2010;303(1):47-53) for more:
http://jeffreydach.com/2010/01/21/jama-says-ssri-antidepressants-are-placebos-by-jeffrey-dach-md.aspx
jeffrey dach md
December 29, 2010 at 4:44 pm
greensleeves
NIH has done a few studies on this, look at their Alternative medicine web site. In a test of tele-medicine, they found that folks do poorly with phone consultations. Video consultations are better, but still not as good as in-person visits, and in-person visits where the doctor touches you are best of all.
Frankly, people are social monkeys and health largely derives from social status. Doctors are high-status folks, and associating with them closely increases your owns status briefly, thus improving your health, even when the doctor just touches you. Just having a higher-status person pay attention to you – even a priest, a teacher, a nurse – should improve people.
The question is how long the effect lasts.
December 29, 2010 at 4:54 pm
greensleeves
Sorry, comment got cut off – The point is that the placebo is a McGuffin. It’s the interaction with high-status person and the amount of the time they devote to you, if they touch you – that’s what works. If you sent folks to the religious figure of their choice – to the priest, nun, rabbi, pastor, lama, imam, shaman – and instead of a sugar pill they got a blessed rosary, a quick prayer, and an arm around the shoulder, they would improve just as much as going to the doctor and getting the sugar pill.
The second question would be – would having a talk with any higher-status person work? Could Warren Buffett or Donald Trump also cure with a handshake and a personally dedicated autographed copy of their latest book?